Well, it ain’t coming anytime soon, that’s for sure. MTV have a posting that says Ron Perlman (Hellboy) has a few reservations about sitting in the makeup chair for hours at a time, as mentioned by Guillermo Del Toro who also says "The heartbreak for me is that I know how it ends and I don't know if I want to see that ending. But I would love to do it."
So who knows, but wouldn’t sometime in 2013 be an interesting date! That’s my guess anyway!